Certainly Donnafugata are worth a look. Their Mille e Una Notte is pretty expensive, but a serious wine. Tancredi is reasonable value.
Others, Malvasia from the Isole eolie (Aeolian Islands) is interesting as a dessert wine (Hauner is decent quality)
Tasca D'Almerita are worth trying
Amongst others. If you get the chance, try the mud baths at Vulcano. There's little else to see there, so it's only worth a half day trip onto somewhere else like Stromboli or Lipari. However the experience is somewhat unusual.
If you make it to Lipari, the Casbah restaurant is pretty good.
Hope you have a great trip